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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VARS
All Species:
23.03
Human Site:
S774
Identified Species:
31.67
UniProt:
P26640
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26640
NP_006286.1
1264
140476
S774
A
A
K
E
F
G
V
S
P
D
K
I
S
L
Q
Chimpanzee
Pan troglodytes
XP_001160008
1264
140384
S774
A
A
K
E
F
G
V
S
P
D
K
I
S
L
Q
Rhesus Macaque
Macaca mulatta
Q5TM74
1064
118624
L641
G
T
Q
L
T
G
R
L
P
F
S
K
V
L
L
Dog
Lupus familis
XP_538837
1256
139671
S774
A
A
K
E
F
G
V
S
S
D
K
I
S
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1Q9
1263
140197
S773
A
A
R
E
F
G
V
S
P
D
K
I
S
L
Q
Rat
Rattus norvegicus
Q04462
1264
140350
S774
A
A
R
E
F
G
V
S
P
D
K
I
S
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520676
985
109386
L563
H
P
F
V
Q
R
T
L
P
V
V
F
D
D
F
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088439
1243
140617
A753
A
A
R
V
F
N
V
A
A
E
K
I
S
L
R
Zebra Danio
Brachydanio rerio
XP_682807
1111
123867
V673
H
D
I
L
F
F
W
V
A
R
M
V
M
M
G
Tiger Blowfish
Takifugu rubipres
P49696
1217
138200
S721
A
A
K
R
F
N
V
S
P
D
K
I
A
L
R
Fruit Fly
Dros. melanogaster
NP_524838
1049
118236
F627
F
W
V
A
R
M
V
F
F
G
Q
K
L
L
G
Honey Bee
Apis mellifera
XP_395202
1043
121057
F621
F
W
V
A
R
M
V
F
L
G
Q
K
L
I
G
Nematode Worm
Caenorhab. elegans
Q9U1Q4
1050
118902
E628
T
G
K
L
P
F
K
E
I
L
L
H
A
M
I
Sea Urchin
Strong. purpuratus
XP_001200958
1119
126755
M687
L
F
F
W
V
A
R
M
V
M
M
G
Q
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93736
1108
125908
G674
V
M
M
G
M
K
L
G
G
E
V
P
F
S
K
Baker's Yeast
Sacchar. cerevisiae
P07806
1104
125751
R673
I
L
F
F
W
V
T
R
M
I
L
L
G
L
K
Red Bread Mold
Neurospora crassa
P28350
1093
123334
T671
I
M
L
S
L
K
M
T
G
E
V
P
F
T
E
Conservation
Percent
Protein Identity:
100
99.5
43.4
92.8
N.A.
93.4
93.4
N.A.
63
N.A.
65.3
45
63.8
50.9
49.1
44.9
44.4
Protein Similarity:
100
99.8
56
95.6
N.A.
96.4
96.3
N.A.
69.8
N.A.
78
58.8
76.8
63.1
63.4
59.5
59.6
P-Site Identity:
100
100
20
93.3
N.A.
93.3
93.3
N.A.
6.6
N.A.
53.3
6.6
73.3
13.3
6.6
6.6
0
P-Site Similarity:
100
100
26.6
93.3
N.A.
100
100
N.A.
6.6
N.A.
80
20
86.6
20
20
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.6
42.6
40.3
Protein Similarity:
N.A.
N.A.
N.A.
58.3
60.1
56
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
42
42
0
12
0
6
0
6
12
0
0
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
6
0
0
0
0
0
0
0
36
0
0
6
6
0
% D
% Glu:
0
0
0
30
0
0
0
6
0
18
0
0
0
0
6
% E
% Phe:
12
6
18
6
48
12
0
12
6
6
0
6
12
0
6
% F
% Gly:
6
6
0
6
0
36
0
6
12
12
0
6
6
0
18
% G
% His:
12
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% H
% Ile:
12
0
6
0
0
0
0
0
6
6
0
42
0
6
6
% I
% Lys:
0
0
30
0
0
12
6
0
0
0
42
18
0
0
12
% K
% Leu:
6
6
6
18
6
0
6
12
6
6
12
6
12
59
12
% L
% Met:
0
12
6
0
6
12
6
6
6
6
12
0
6
12
0
% M
% Asn:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
6
0
0
6
0
0
0
42
0
0
12
0
0
0
% P
% Gln:
0
0
6
0
6
0
0
0
0
0
12
0
6
6
30
% Q
% Arg:
0
0
18
6
12
6
12
6
0
6
0
0
0
0
12
% R
% Ser:
0
0
0
6
0
0
0
36
6
0
6
0
36
6
0
% S
% Thr:
6
6
0
0
6
0
12
6
0
0
0
0
0
6
0
% T
% Val:
6
0
12
12
6
6
53
6
6
6
18
6
6
0
0
% V
% Trp:
0
12
0
6
6
0
6
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _